Searchable abstracts of presentations at key conferences in endocrinology

ea0067o2 | Oral Presentations | EYES2019

Occurrence of second primary malignancy in medullary thyroid cancer (MTC) patients

Simeakis George , Saltiki Katerina , Zapanti Evangelia , Kassis Evanthia , Alevizaki Maria

Objectives: Coexistence of two different malignancies is frequently reported. Sometimes occurs in the context of well-established syndromes like MEN2. Rearranged during transfection (RET), is an oncogenic driver activated in different kinds of neoplasias such as: MTC, Differentiated Thyroid Cancer (DTC), Non-Small Cell Lung Cancer (NSCLC). We have previously reported an increased prevalence of DTC in familial MTC patients carrying the RET (G533C) mutation. Ai...